Chiu Ping Cheng Professor
Biology, University of Minnesota, USA
Specialty: Molecular Biology, Plant-Microbe interactions
Laboratory: Life Science Building R942
Current Research Interests
The interactions among Solanaceaous plants, Ralstonia solanacearum (the causal bacterium of bacterial wilt) and biocontrol agents.
Plants constantly encounter a wide range of diseases, leading to tremendous crop losses. Plant bacterial wilt (BW), caused by Ralstonia solanacearum, is a deadly and complex soil-borne vascular disease of many agronomically important crops worldwide. Control for this disease via traditional practices has been very ineffective. To gather important information and resources potentially useful for disease control, our researches aim to gain insights into molecular mechanisms and signaling pathways involved in the interactions among plants, R. solanacearum and biocontrol agents. Through systematic genomic screening, we currently focus on studying the functions and the involved mechanisms of a group of plant and R. solanacearum genes which play crucial roles in plant-pathogen interactions. In addition, resources have been collecting from tentative biocontrol agents, including bacteriophages and symbiotic fungi.Current projects
Regulatory mechanisms and applications of tomato genes with crucial roles in defense against R. solanacearum and other pathogens.
Functions and regulatory mechanisms of a group of uncharacterized plant E3 ligases.
Applications and the involved mechanisms of bacteriophage-derived proteins and symbiotic fungi in promoting defense of Solanaceaous plants against a broad-spectrum of pathogens.
Regulatory mechanisms and applications of R. solanacearum genes with determining roles in bacterial virulence.
Ting HM, Cheah BH, Chen YC, Yeh PM, Cheng CP, Yeo FKS, Vie AK, Rohloff J, Winge P, Bones AM, Kissen R (2020) The role of a glucosinolate-derived nitrile in plant immune responses. Frontiers in Plant Science 11: 257.
Hsuan-Ju Tsai, Ko-Hsuan Shao, Ming-Tsair Chan, Chiu-Ping Cheng, Kai-Wun Yeh, Ralf Oelmüllere, Shu-Jen Wang* (2020) Piriformospora indica symbiosis improves water stress tolerance of rice through regulating stomata behavior and ROS scavenging systems Plant Signaling and Behavior 15(2):1722447.
Hsiao PY, Cheng CP*, Koh KW, and Ming-Tsair Chan* (2017) The Arabidopsis defensin gene, AtPDF1.1, mediates defence against Pectobacterium carotovorum subs. Carotovorum via an iron-withholding defence system. Scientific Reports 7: 9175 | DOI: 10.1038/s41598-017-08497-7. (SCI)
Liu AC, and Cheng CP* (2017) Pathogen-induced ERF68 regulates hypersensitive cell death in tomato. Molecular Plant Pathology18: 1062-1074. (SCI)
Wang K , Remigi P, Anisimova M , Lonjon F , Kars I , Kajava A , Li CH , Cheng CP , Vailleau F , Genin S , Peeters N (2016) Functional assignment to positively selected sites in the coretype III effector RipG7 from Ralstonia solanacearum . Molecular Plant Pathology17: 553-564 (SCI)
Chien-Hui Li, Kuan-Chung Wang, Yu-Hau Hong, Tai-Hsiang Chu, Yu-Ju Chu, I-Chun Chou, Der-Kang Lu, Chao-Yen Chen, Wen-Chieh Yang, and Chiu-Ping Cheng * (2014) Roles of different forms of lipopolysaccharides in Ralstonia solanacearum pathogenesis. Molecular Plant-Microbe Interactions 27:471-478. (SCI)
Yu-Mei Lin#, Shu-Lein Shih#, Wan-Chi Lin, Jia-Wei Wu, Ya-Ting Chen, Chi-Ying Hsieh, Li-Ching Guan, Lu Lin, and Chiu-Ping Cheng* (2014) Phytoalexin biosynthesis genes are regulated and involved in plant response to Ralstonia solanacearum infection. Plant Science 224: 86-94. (SCI) (# equal contribution)
Yu-Hau Hong#, Chi Huang#, Kuan-Chung Wang, Tai-Hsiang Chu, Chien-Hui Li, Yu-Ju Chu, and Chiu-Ping Cheng* (2014) Mutations in Ralstonia solanacearum loci involved in lipopolysarccharide biogenesis, phospholipid trafficking and peptidoglycan recycling render bacteriophage infection. Archives of Microbiology 196: 667-674. (SCI) (# equal contribution)
Pin-Yao Huang, Yu-Hung Yeh, An-Chi Liu, Chiu-Ping Cheng*and Laurent Zimmerli* (2014) The Arabidopsis LecRK-VI.2 associates with the pattern-recognition receptor FLS2 and primes Nicotiana benthamiana pattern-triggered immunity . Plant Journal 79: 243-255. (SCI)
Wen-Chieh Yang#, Yu-Mei Lin#, Yi-Sheng Cheng, and Chiu-Ping Cheng* (2013) Ralstonia solanacearum RSc0411 (lptC) is a determinant for full virulence and has a strain-specific novel function in the T3SS activity . Microbiology-SGM 159:1136–1148. (# equal contribution) (SCI)
WY Kuo#, CH Huang#, AC Liu, CP Cheng, SH Li, WC Chang, C. Weiss, A. Azem and TL Jinn* (2013) CHAPERONIN 20 mediates iron superoxide dismutase (FeSOD) activity independent of its co-chaperonin role in Arabidopsis chloroplasts. New Phytologist 197:99-110. (# equal contribution) (SCI)
Chi-Yin Hsieh, Jaw-Fen Wang, Pei-Cheng Huang, Der-Kang Lu, Yu-Mei Lin, Wen-Chieh Yang, Chiu-Ping Cheng* (2012) Ralstonia solanacearum nlpD (RSc1206) contributes to host adaptation.European Journal of Plant Pathology 133:645–656. (SCI)
Chia-Wen Li, Ruey-Chih Su, Chiu-Ping Cheng, Sanjaya, Su-Juan You, Tsai-Hung Hsieh, To-Chun Chao, and Ming-Tsair Chan*. (2011) Tomato RAV transcription factor is a pivotal modulator involved in the AP2/EREBP-mediated defense pathway. Plant Physiology 156:213–227. (SCI)
I-Chun Pan, Chia-Wen Li, Ruey-Chih Su, Chiu-Ping Cheng, Choun-Sea Lin and Ming-Tsair Chan. (2010) Ectopic expression of an EAR motif deletion mutant of SlERF3 enhances tolerance to salt stress and Ralstonia solanacearum in tomato. Planta 232:1075-1086.. (SCI)
Tsai-Hung Hsieh, Chia-Wen Li, Ruey-Chih Su, Chiu-Ping Cheng, Sanjaya, Yi-Chien Tsai, Ming-Tsair Chan. (2010) A tomato bZIP transcription factor, SlAREB, is involved in water deficit and salt stress response. Planta 231:1459-1473. (SCI)
Rajendran Senthilkumar, Chiu-Ping Cheng and Kai-Wun Yeh*. (2010) Genetically pyramiding protease inhibitor genes for dual broad-spectrum resistance against insect and phytopathogens in transgenic tobacco. Plant Biotechnology Journal 8: 65-75. (SCI)
Fang-I Ho, Yong-Yi Chen, Yu-Mei Lin, Chiu-Ping Cheng* and Jaw-Fen Wang*. (2009) A Tobacco rattle virus-induced gene silencing system for soil-borne vascular pathogens using Rasltonia solanacearum as an example. Botanical Studies 50:413-424. (SCI)
Yong-Yi Chen, Yu-Mei Lin, To-Chun Chao, Jaw-Fen Wang, An-Chi Liu, Fang-I Ho, and Chiu-Ping Cheng reveal*. (2009) Virus-induced gene silencings the involvement of ethylene -, salicylic acid- and mitogen-associated protein kinase related defense pathways in the resistance of tomato to bacterial wilt. Physiologia Plantarum 136:324-335. (SCI)
Chiu-Ping Cheng* and Yu-Ju Chu. (2009) Effects of environmental factors on the multiplication and survival of a Taiwan Ralstonia solanacearum tomato strain. Taiwania 54:37-44.
Yu-Mei Lin, I-Chun Chou, Jaw-Fen Wang, Fang-I Ho, Yu-Ju Chu, Pei-Cheng Huang, Der-Kang Lu, Hwei-Ling Shen, Mounira Elbaz, Shu-Mei Huang, Chiu- Ping Cheng*. (2008) Transposon mutagenesis reveals differential pathogenesis of Ralstonia solanacearum on tomato and Arabidopsis. Molecular Plant-Microbe Interactions 21:1261-70. (SCI)
Yu-Mei Lin, I-Chun Chou, Chiu-Ping Cheng*. (2008) A highly efficient bioassay system for screening Ralstonia solanacearum mutants with altered virulence. Taiwania (in press ).
Ervin D. Nagy, Tso-Ching Lee, Wusirika Ramakrishna, Zijun Xu, Patricia E. Klein, Phillip SanMiguel, Chiu-Ping Cheng, Jingling Li, Katrien M. Devos, Keith Schertz, Larry Dunkle, Jeffrey L. Bennetzen. (2007 ) Fine mapping of the Pc locus of Sorghum bicolor, a gene controlling the reaction to a fungal pathogen and its host-selective toxin. Theoretical and Applied Genetics 114:961–970. (SCI)
YL Chan, V. Prasad, Sanjaya, KH Chen, PC Liu, MT Chan, and CP Cheng*. (2005) Transgenic tomato plants expressing an Arabidopsis thionin (Thi2.1) driven by fruit-inactive promoter battles against phytopathogenic attack. Planta 221:386-393. (SCI)
WC Lin, ML Cheng, JW Wu, NS Yang, and CP Cheng*. (2005) A glycine-rich protein gene family predominantly expressed in tomato roots, but not in leaves and ripe fruit. Plant Science 168: 283-295. ( SCI)
WC Lin, CF Lu, JW Wu, ML Cheng, YM Lin, NS Yang, L. Black, SK Green, JF Wang, and CP Cheng*. (2004) Transgenic tomato plants expressing the Arabidopsis NPR1 gene confer enhanced resistance to a spectrum of fungal and bacterial diseases. Transgenic Res. 13: 567-581. (SCI)
IC Chou, NE Olszewski, and CP Cheng*. (2004) Generation of random, in-frame mutations by TN1000-mediated mutagenesis. Journal of Genetics and Molecular Biology 15:137-142.
KY Hwang, IC Chou, YM Lin, and CP Cheng*. (2004) Plant age-related resistance to Ralstonia solanacearum, the causal agent of bacterial wilt. Journal of Genetics and Molecular Biology 15:108-115.
HL Liu, ML Cheng, CG Tong, NS Yang, MT Chan, and CP Cheng. (2003) In silicoidentification and phylogenetic analysis of putative plant arylalkylamine N-acetyltransferase. Journal of Genetics and Molecular Biology 14:213-223.
WC Lin, JW Wu, HL Liu, ML Cheng, CJ Peng, JF Wang, Peter Hanson, and CP Cheng*. (2001) Introduction of defense genes that confer broad-spectrum disease-resistance into tomato plants. In: Tzeng DDS and Huang JW (ed) Proceedings of International Symposium on Biological Control of Plant Diseases for the New Century – Mode of Action and Application Technology, Department of Plant Pathology, National Chung Hsing University (ISBN:957-02-9957-6), pp 225 -237. (Invited speaker)
WM Chen, TM Lee, CC Lan, and CP Cheng*. (2000) Characterization of halotolerant rhizobia isolated from root nodules of Canavalia rosea from seaside areas. FEMS Microbiology Ecology 34:9-16. (SCI)
CP Cheng, BEL Lockhart, and NE Olszewski. (1998). Tubules containing virus particles are present in plant tissues infected with Commelina yellow mottle badnavirus. Journal General Virology79:925-929. (SCI)
CP Cheng, BEL Lockhart, and NE Olszewski. (1996 ). The ORF I and II protein of Commelina yellow mottle virus are virion-associated. Virology 223:263-271. (SCI)
CP Cheng, CT Chen, TC Deng, and HJ Su. (1993) Monoclonal antibodies against sugarcane mosaic virus. Plant Pathology Bulletin 2:227-231. (SCI )
Advanced plant molecular biology
Biotechnology core techniques